You're bang on that CRC's are a Layer 1 or Layer 2 issue. Most commonly it's dirty/loose/broken cables, or occasionally a bad SFP/switchport. It can also be due to MTU mismatch. If it's a 10Gb fiber link, interference is highly unlikely as fiber is relatively unaffected by RF as opposed to copper. In terms of the consistency in timing, a couple of things to note are: - Higher CRC counts will generally correlate with higher network traffic (more packets = more likely for one to be corrupted). Is it possible that at these times the link had a higher utilization in general? - Do you have any scheduled traffic around those times where higher MTU data is being sent (and where a mismatch might be present in the network)? In any circumstance, I would definitely suggest starting with swapping out the cable and continue troubleshooting up the stack from there.
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