My company is also running Meraki Client VPN and Microsoft Dynamics and using the MS Win 10 built-in VPN client. I've recently found that when they have problems connecting to the MS dynamics Server (or any other network resource), the quickest 'solution' is to rebuild the VPN connection. One could either do so manually, (which can go relatively quickly) or fellow Meraki users have created PowerShell or other scripts to assist with most of the rebuild process. (I'd search these forums for 'client VPN setup script').
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Set-VpnConnection -Name "ConnectionName" -ServerAddress WAN Public IP -AuthenticationMethod Pap -DnsSuffix AD domain name -EncryptionLevel Optional -Force -L2tpPsk VPNPSK -RememberCredential $true -TunnelType L2tp
Add-VpnConnection -Name "Connection Name" -ServerAddress WANPublicIP -AuthenticationMethod Pap -DnsSuffix ADDSdomainName -EncryptionLevel Optional -Force -L2tpPsk VPNPSK -RememberCredential -TunnelType L2tp -AllUserConnection
Set-ItemProperty HKLM:\SYSTEM\CurrentControlSet\Services\PolicyAgent -Name AssumeUDPEncapsulationContextOnSendRule -Value 2 -Type DWord These scripts will do most of creation, but you'll still have to set certain things (like the user credentials, and such) manually. I've also found the DISABLING IPv6 on the VPN adapter also helps with vpn connectivity.
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