Thank you very much to all for the information and the tips sent, analyzing in depth I chose to place in the option of Block/white URL's of the policy: APPEND. With this when the client requests a massive change I use an API that adds the URL (block / white) in the general content filtering and with this applies to the group policy that has been created in each Meraki. Of course in this time I have to enter one by one on each device to add the config however for the future it will no longer be necessary.
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