You have to use the same type of optics at each end of a fibre (and I am assuming this is a private point-to-point fibre, rather than something provided by a service provider). If you use LR at one end, you have to use LR at the other end. You might need to use different part numbers for different device models. This is the Meraki SFP compatibility matrix. This tells you what you can use on each device, fibre length restrictions, the laser wavelength, etc. You consult this for the MX105 end. "MA-SFP-10GB-LR" is a valid option for the MX105. https://documentation.meraki.com/Platform_Management/Product_Information/Overviews_and_Datasheets/Small-Form_Factor_Pluggable_(SFP)_and_Stacking_Accessories This is the same thing for a 4500x. Without looking it up, it is likely you should be using "SFP-10G-LR" or "SFP-10G-LR-S" for the 4500x. "MA-SFP-10GB-SR" is not likely to be a supported option for a 4500x. https://tmgmatrix.cisco.com/ If you want to use an unsupported SFP in a 4500x, then you'll need to use these commands (on the 4500x) to disable the checks. service unsupported-transceiver
no errdisable detect cause gbic-invalid
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