Don't you know how to create a L3 security rule? https://documentation.meraki.com/MX/Firewall_and_Traffic_Shaping/MX_Firewall_Settings#Outbound_rules
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Check the documentation. https://documentation.meraki.com/MX/Content_Filtering_and_Threat_Protection/URL_Block_List_and_Allow_List_Patterns
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No reality, you can use the anyconnect to manage your wifi connection. Take look at this https://community.cisco.com/t5/wireless-mobility-knowledge-base/anyconnect-secure-mobility-client-3-0-network-access-manager-amp/ta-p/3123926
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