When the MS250's uplink was connected to a Cisco switch, I needed to specify a native VLAN for MS250's interface for traffic to flow. I was assuming the Cisco router would behave in the same way, so when the MS250's uplink was connected to the router, it would need the native VLAN defined. Sadly traffic wouldn't flow. When I removed the native VLAN from the MS250's uplink port and connect it to the Cisco router, everything started working.
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