My main comment would be, why are you replacing a 5516 with an MX84? Both devices are announced EOL in 2026 and the 5516 provides more throughput and features. I can certainly see if your setup is simple enough migrating from ASA to MX, but I would want to be implementing a current model so I don't have to change things again in just over a year. For STP I encourage you to read this article: https://documentation.meraki.com/MS/Port_and_VLAN_Configuration/Configuring_Spanning_Tree_on_Meraki_Switches_(MS) There is example code for IOS interoperability and an overall section on interoperability. I can't speak specifically to an environment such as yours you would have to consult the documentation for each vendor/operating system. Regarding your comment about the ports connecting the firewalls to the switches, yes the trunking settings will have to match. I don't have a specific recommendation as it's really an either or scenario. One side you will have to change and one side you won't. It doesn't IMO matter which one. Honestly my biggest recommendation is perhaps work with your partner or account manager and get some engineering assistance. You have a somewhat complex environment and I'm guessing based on the Nexus switches perhaps some mission critical items. What you want to do is definitely doable but may require more detail to properly plan than we can realistically provide here.
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