Hi John,
What are your requirements? The main benefit of Wi-Fi 6 is efficiency in high density deployments. Being a 4x4:4 wave 2 AP, the MR52 is more than capable, but it's understandable wanting to future-proof yourself. There are not many Wi-Fi 6 clients out there yet so the benefits won't be realized for probably another year.
There were some issues with certain clients when the MR45/55 first came out because users hadn't updated their NIC drivers to support the new 802.11ax information elements, but the same thing happened when 802.11ac and 802.11n came out. It takes two radios to tango and with any new infrastructure technology, the clients will often times need updates too. At this point, most modern devices have updates available and it's not an issue. If you go for the MR45 and do have clients that have trouble with 802.11ax though, the option does exist to disable it on the Wireless > Configure > Radio settings > RF profiles.
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