Is your server in the cloud or is it on premise? In fact, it is not the role of the firewall to block spam. you can block the ip, but do not forget that usually an email server can have more than one IP, especially if it is in the cloud. Maybe you have to review your concepts.
I am not a Cisco Meraki employee. My suggestions are based on documentation of Meraki best practices and day-to-day experience.
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