Hey Fucomyoo, I have a case open with Meraki regarding this.. It is the exact same experience we had with version 15 and 16 of firmware when you enabled the "Full list" option in content filtering. In version 17 there is no option to select "Top list" or "Full List" since they moved from "Bright cloud" to " Cisco Talos Intelligence" so my first thought is that they are now using the process for "Full list" as standard. This heavily leans on the MX cache to speed things up (we are running MX 250) I'm not sure how long the cache TTL is (how long a record stays in the cache) or how large the cache is (how many records are kept until they are cycled in for newer results) regardless of this though.. its the initial lookup of the site that is slow.. so cache wont make a difference until after the first lookup. As we speak the Meraki support agent just captured a "slow" site lookup... ill keep you posted.
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