Hi @henleyjj our ISE was running 2.7.0.356 with patches 2,4,5 and it now running patch 7 however the issue for us turned out to be caused by the bonjour service, once this was disabled we no longer experienced issues. Unsure if the symptoms you are experiencing are the same as ours, I also have a post on the Cisco ISE community regarding our issue with a break down of the symptoms we had. https://community.cisco.com/t5/network-access-control/ios-device-re-auth-after-wakeup-on-meraki-ise/m-p/4585342#M573872 Hope you get your issue resolved
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