All Meraki switches come with all their ports set to VLAN 1 and Trunks with No ACL's to stop intercommunication between clients. To answer your question, should PC>Merak Switch>PC on port 443 work, the answer is yes. If there is a firewall in-between the two clients, definitely check that Port 443 is open to allow communication between the two clients. Alternatively also check that there are no host-based firewalls which could be stopping communication on port 443.
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