Ok let me try to explain better.
I do not have ISE since its an additional cost I would get this if I could but right now I am just using Meraki MX.
The aim is just to isolate the traffic from one endpoint/endpoints with a group policy applied so that it only goes to one VPN client/clients with a group policy also applied.
I cannot isolate the traffic because the group policy only supports IP addresses.
Any traffic I allow from the endpoints group policy has to go to the entire IP subnet for VPN clients.
This is because I would have to change the specific IP addresses allowed for the endpoint group policy each time the VPN clients IP's change since they randomly do so upon VPN connection.
If I could just say allow traffic going to these group policy tagged clients then it would work easy without static IP.
As far as I have seen there is no feature for that for Meraki MX VPN clients.