We woke up this morning to clients unable to access Office 365 and Cisco Duo. Cisco Meraki has posted about this in the community, but we can't reply with additional information because it is a service notice. So you can do this here if you have other apps break.
https://community.meraki.com/t5/Meraki-Service-Notices/Microsoft-vulnerability-and-IPS-SNORT/ba-p/15...
Cisco Duo was probably worse for us, as it prevented users from being able to log into their computers or access any corporate app.
If you are still experiencing this issue, turn IPS off, click save, and turn it back on again. This will get you the new signature immediately.
Anyone else with apps that broke feel free to reply.