Yes the MS250 will be able to connect.  To guarantee you have no support issues you would need to use fibre (10GbeSR)   But I suspect either the HP or the Meraki TwinAx 3m cable will be 99% likely to work.   If you are using 10GBaseT you could also consider using the MS350-24X, which includes 8 x MGig ports. MGig ports also do 10GBaseT. https://meraki.cisco.com/products/switches/ms350-24x     Also note you really want to be using SFP+ to connect servers, rather than 10GBaseT.  10GBaseT has about 100 times more latency than SFP+, and this will impact anything that does lots of transactions, like databases and storage. ... View more