You know that when it is in NAT mode the client uses the AP's IP for communication, so if you have a Firewall rule that restricts the network the AP is on, that is a possible explanation.
Let us know a little more about your network, do you have a firewall that filters content?
I am not a Cisco Meraki employee. My suggestions are based on documentation of Meraki best practices and day-to-day experience.
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