As an update, Meraki has looked into this issue, and said this is normal. I don't see how millions of packet drops over the course of week/month is a normal thing, but I have no way to prove otherwise.
Coming from a Cisco Catalyst background, 100k+ packet drops over a day/week would be a high cause for concern, or at least worth looking into to see what is causing it. The main question is does this have an effect on performance? No, not that I can prove. Other than me seeing a number on a page, I cannot gather any additional information on what is happening. I have checked all of the Meraki docs in regard to best practices on MS, and those have been applied. It does appear to be better, but still high at times. Since its random, I cant get a packet capture to see from the switch, other than normal traffic.
Iperf tests between ports, and L3 boundaries appear fine (on the same 425 port to port) and on the uplinks from the 425 to the 9300. No errors on the physical ports on either switch (for uplinks or trunked ports). Nothing in the event logs for either device. Errors are not incrementing when performing the tests, so whatever is going on is specific to the management traffic.