Hello everyone, 
 
I have been getting mixed answers and want to confirm this topology. 
Am I able to have a MX250 HA pair, LACP to MX425-16 by SFP+. Then run QSFP+ 40G from the MS425-16 Uplink to the MS450-12 40G ports as the QSFP28 ports don’t lower link speeds and also is an uplink port. Using MTP OS2 or OM5 jumpers. 
Then trunking 40G QSFP+ to all my MS390-48UX’s. 
Will this work or I am skipping over a thought? 
Thanks much for your time understanding…