If it's a single site that sort of weird it works and sometimes doesn't issue can sometimes be ISP related. I usually see it on coax services. I've had to reboot modems at times for Comcast, Spectrum, and maybe others and there is not much you can do to prevent it.
As to alternative configs that might help, perhaps open a TAC and Meraki support case and ask them to collab on it if no one else is able to provide any specific suggestion. The settings you are mentioning are definitely tweaks I've seen and heard of, I just don't deal with it frequently enough to have a specific idea.
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