What MX firmware are you running? Auto detect is preferred unless there is a compelling reason to change the speed/duplex.
Duplex mismatches affecting physical link speed
When interconnecting two Ethernet peers, Meraki recommends using auto-negotiation, which allows Ethernet peers to exchange link speed and duplex information.
Explanation:
Ethernet peers use electrical signals to determine when a link is established. These electrical pulses make up a 16-bit word defining the speed and duplex for auto-negotiation. If the speed and duplex of one peer must be manually set, it is important to set the other peer with the same settings.
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