Cisco Secure Client cannot establish a connection

[MFG]

When trying to connect using the latest version of Cisco Secure Client to our MX appliance, some clients using Windows 11 will successfully authenticate to the VPN using A/D credentials, however, they get an error 

The certificate on the secure gateway is invalid.  A VPN connection could not be establishted

followed by

Cisco Secure Client was not able to establish a connection to the specified secure gateway

I have exported the Windows A/D server certificate and imported it to the local cert manager on the client. 

I am assuming the secure gateway is the Windows A/D server, but am not sure.  We are using Windows Server 2022 Standard.  

I do see some errors on the A/D server relating to TLS.  It appears to be enabled based on the gpedit.   I do not think SSL is enabled on the server but not sure if that is a requirement.

What other things can I check?

[MFG]

The other thing is it isn't all clients.   The majority are connecting without any issue

[PhilipDAth]

>The certificate on the secure gateway is invalid.

Are you using the AnyConnect auto-generate certificate on the MX.  If so, are you connecting to the dynamic DNS name?  If not, you'll get this error.