I don't know if you can configure the home page. You can configure managed bookmarks though.
You need to load some content like the below into Systems Manager (as a managed bookmark).
{
"kind": "androidenterprise#managedConfiguration",
"productId": "app:com.android.chrome",
"managedProperty": [
{
"key": "EditBookmarksEnabled",
"valueBool": false
},
{
"key":"ManagedBookmarks",
"valueString": "[{\"toplevel_name\":\"Contoso Bookmarks\"},{\"url\":\"microsoft.com\",\"name\":\"Microsoft\"},{\"url\":\"blogs.technet.microsoft.com\",\"name\":\"Favourite Blogs\"},{\"name\":\"Email services\",\"children\":[{\"url\":\"gmail.com\",\"name\":\"GMail\"},{\"url\":\"outlook.com\",\"name\":\"Outlook\"}]}]"
}
]
}