I was able to configure this with my Identity provider (Okta) so RADIUS automatically sends a push notification, but that is the extent of getting 2FA with RADIUS working.  The follow-up prompt as seen with ASA just doesn't exist in the Meraki implementation, just as the ability to deploy the AnyConnect client from the firewall is missing.     SAML also worked as an option.  https://documentation.meraki.com/MX/AnyConnect_on_the_MX_Appliance/Authentication/AnyConnect_VPN_Okta_SAML_Configuration  there are other provider write ups as well.    https://documentation.meraki.com/MX/AnyConnect_on_the_MX_Appliance/AnyConnect_Troubleshooting_Guide/AnyConnect_SAML_Troubleshooting_Guide  ... View more