The 'best' way to do it will depend on exact details/context.   I suggest look at switch templates and port profiles to see if using them would solve all/part of what you want to do...   https://documentation.meraki.com/Architectures_and_Best_Practices/Cisco_Meraki_Best_Practice_Design/Best_Practice_Design_-_MS_Switching/Templates_for_Switching_Best_Practices   https://documentation.meraki.com/MS/Port_and_VLAN_Configuration/Switch_Port_Profiles   The API can also be used with these.   Within the API, action batches a possible way to be more efficient when making a lot of changes...   https://developer.cisco.com/meraki/api-v1/action-batches-overview/   ... View more