I just want to chime in on the fact you said they are stacked using 10 Gbps. MS225's do physical stacking and those cables are 40 Gbps each, not 10 Gbps. But to help you with your post: If you don't use port-channels on your ESXi hosts and just divide your VM's manually over your VMNIC's you would be better off using separate access switches to those hosts. You could do the separate network like Philip suggests or if you want to keep it in the same network you could do staged upgrade. If you do port channels and want separate switch upgrades then you would not be helped with Meraki switches but you would have needed vPC's on Nexus switches if you like to keep it in classical layer 2 networking.
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