>Should I change the MTU settings on the switches?
No.
This could start a religious discussion. The performance is directly proportional to latency and MTU. If the latency is low (such as over a pure LAN) then going from 1500 to 9000 byte frames makes little differences.
If the latency is high then a larger MTU can make quite a difference.
The only special case is if you are using iSCSI. If you are (say) using iSCSI and using 4K IO blocks then you might consider using a larger MTU so that each disk block can be transmitted in a single packet - but make sure that everything on the path can support that MTU.
Typically unless you are doing something transactional (such as SQL server doing lots of small transactions) you will have trouble measuring the performance difference.
Personally, I avoid using iSCSI in preference to NFS or SMB, because the setup it so much simpler, and generally if you touch none of the settings (and it is a LAN) you'll just get good results.